Polygenic sex determination

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Polygenic sex determination

What is sex determination? Sex determination is the mechanism by which sexual organisms direct gonad development towards distinct but reproductively compatible outcomes. Molecular signaling cascades in the developing gonad provide instructions to the tissue to develop as male or female (or in some cases hermaphrodite), and these signals can be initiated in different ways. Sex can be determined ...

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Polygenic Sex Determination System in Zebrafish

BACKGROUND Despite the popularity of zebrafish as a research model, its sex determination (SD) mechanism is still unknown. Most cytogenetic studies failed to find dimorphic sex chromosomes and no primary sex determining switch has been identified even though the assembly of zebrafish genome sequence is near to completion and a high resolution genetic map is available. Recent publications sugges...

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On the Instability of Polygenic Sex Determination: the Effect of Sex-specific Selection.

A combination of analytical and simulation models is used to explore the initial evolution of genic sex determination from polygenic sex determination. Prior studies have indicated that polygenic sex determination is rare or absent in extant species but that it has likely played an important intermediate role in the evolution of other genetic sex-determination systems. This study explores why p...

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The Evolution of Polygenic Sex Determination with Potential for Environmental Manipulation

We present a formal account of a genetic mechanism for Environmental Sex Determination (ESD) using a probabilistic process algebra (WSCCS). We exploit the process algebra to demonstrate that a single chromosome pair based polyfactorial system is intrinsically unstable. The system evolves, with a deterministic relationship between an animal's sex and its polyfactor count, to three possible forms...

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A polygenic hypothesis for sex determination in the European sea bass Dicentrarchus labrax.

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ژورنال

عنوان ژورنال: Current Biology

سال: 2013

ISSN: 0960-9822

DOI: 10.1016/j.cub.2013.04.004